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IMS Research

Infrared Imaging In Breast Cancer

Authors: Parvis Gamagami, M.D., Melvin J. Silverstein, M.D., James R. Waisman, M.D.

Published: 1997

Abstract:
In 1982, inspired by the notion of angiogenesis in experimentally transplanted cancer in animals showing that a small transplanted cancer could not "take" in the recipient organ unless tumor angiogenesis was established. We undertook a clinical research in 530 breast cancer patients who had previous mammography to see whether angiogenesis could be seen on mammography in early breast cancer and if so, could it have any impact on the detection of early breast cancer. Furthermore, we studied angiogenesis by infra-red imaging camera in a large number of symptomatic and asymptomatic patients, in 148 non-palpable cancers and in 20 inflammatory breast carcinomas.

We found the following:

1. Angiogenesis was the first sign appearing on mammography before the appearance of image of breast cancer, predicting in 91 % of the cases which breast might develop breast carcinoma. This is an important finding in the detection of the early stages of breast cancer development.

2. Infra-red imaging goes hand in hand with mammography. Hypervascularity and hyperthermia could be shown in 86% of non-palpable breast cancer. In 15% it helped to detect the cancer upon an unsuspicious image on mammography.

3. Infra-red imaging was found to be the only test showing the efficiency of chemotherapy in inflammatory breast carcinoma.


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